Gabapentin 600mg, 800mg – Glenmark Pharmaceuticals Inc.

G 31 (Gabapentin 600 mg)

Pill with imprint G 31 is White, Elliptical/Oval and has been identified as Gabapentin 600 mg. It is supplied by Glenmark Generics Inc.

Gabapentin is used in the treatment of postherpetic neuralgia; epilepsy and belongs to the drug class gamma-aminobutyric acid analogs. Risk cannot be ruled out during pregnancy. Gabapentin 600 mg is not a controlled substance under the Controlled Substances Act (CSA).

Gabapentin

Imprint

G 31

Strength

600 mg

Color

White

Size

17.00 mm

Shape

Elliptical/Oval

Availability

Prescription only

Drug Class

Gamma-aminobutyric acid analogs

Pregnancy Category

C – Risk cannot be ruled out

CSA Schedule

Not a controlled drug

Labeler / Supplier

Glenmark Generics Inc.

Inactive Ingredients

corn starch, copovidone, poloxamer 407, magnesium stearate, titanium dioxide, magnesium silicate, polysorbate 80, water

Note: Inactive ingredients may vary.

Labelers / Repackagers

NDC Code	Labeler / Repackager
68462-0126	Glenmark Pharmaceuticals Inc.
54868-5219 (Discontinued)	Physicians Total Care Inc. (repackager)
54569-5956	A-S Medication Solutions, LLC (repackager)
33261-0051	Aidarex Pharmacuticals, LLC (repackager)

G 13 (Gabapentin 800 mg)

Pill with imprint G 13 is White, Elliptical/Oval and has been identified as Gabapentin 800 mg. It is supplied by Glenmark Generics Inc.

Gabapentin is used in the treatment of postherpetic neuralgia; epilepsy and belongs to the drug class gamma-aminobutyric acid analogs. Risk cannot be ruled out during pregnancy. Gabapentin 800 mg is not a controlled substance under the Controlled Substances Act (CSA).

Gabapentin

Imprint

G 13

Strength

800 mg

Color

White

Size

19.00 mm

Shape

Elliptical/Oval

Availability

Prescription only

Drug Class

Gamma-aminobutyric acid analogs

Pregnancy Category

C – Risk cannot be ruled out

CSA Schedule

Not a controlled drug

Labeler / Supplier

Glenmark Generics Inc.

Inactive Ingredients

corn starch, copovidone, poloxamer 407, magnesium stearate, titanium dioxide, magnesium silicate, polysorbate 80, water

Note: Inactive ingredients may vary.

Labelers / Repackagers

NDC Code	Labeler / Repackager
68462-0127	Glenmark Pharmaceuticals Inc.
54868-5195 (Discontinued)	Physicians Total Care Inc. (repackager)

Can I Take Gabapentin When I Take Other Medicines and Herbal Supplements ?

Some medicines may affect how gabapentin works or increase the chance of you having side effects.

Antacids are medicines that counteract (neutralise) the acid in your stomach to relieve indigestion and heartburn.

They come as a liquid or chewable tablets and can be bought from pharmacies and shops without a prescription.

When antacids are used

Antacids may help if you have:

- indigestion
- heartburn or acid reflux – also known as gastro-oesophageal reflux disease (GORD)
- a stomach ulcer
- gastritis (inflammation of the stomach lining)

They can quickly relieve your symptoms for a few hours. But they do not treat the underlying cause and long-term use is not recommended.

Common types of antacids

Many different types of antacid are available. Some are sold under a brand name and others are named after their main ingredient. Brands include Gaviscon (alginic acid) and Pepto-Bismol (bismuth subsalicylate).

Ingredients to look for include:

- - aluminium hydroxide
  - magnesium carbonate
  - magnesium trisilicate
  - magnesium hydroxide
  - calcium carbonate
  - sodium bicarbonate

Some antacids also contain other medicines, such as an alginate (which coats your gullet with a protective layer) and simeticone (which reduces flatulence).

Antacids can reduce the amount of gabapentin that the body takes in so it does not work as well. To stop this happening, if you need to take an antacid, take it at least 2 hours before or after your dose of gabapentin.

Tell your doctor if you’re taking any of these medicines before you start gabapentin treatment:

- - strong painkillers, such as morphine – these can make you very tired and dizzy when you start taking gabapentin
  - antidepressants, such as amitriptyline or fluoxetine
  - antipsychotic medicines for mental health problems like schizophrenia or bipolar disorder
  - a medicine to prevent malaria called mefloquine

Mixing gabapentin with herbal remedies or supplements

Taking herbal remedies and supplements that can make you feel dizzy or drowsy while you’re taking gabapentin could make these side effects worse.

Potential issues with herbal medicines

If you’re taking, or plan to take, any herbal medicines, be aware of the following:

- They may cause problems if you’re taking other medicines. They could result in reduced or enhanced effects of the medicine, including potential side effects.
- You may experience a bad reaction or side effects after taking a herbal medicine.
- Not all herbal medicines are regulated. Remedies specially prepared for individuals don’t need a licence, and those manufactured outside the UK may not be subject to regulation.
- Evidence for the effectiveness of herbal medicines is generally very limited. Although some people find them helpful, in many cases their use tends to be based on traditional use rather than scientific research.

Certain groups of people should be particularly wary of taking herbal medicines.

Who should avoid herbal medicines?

Taking a herbal medicine may not be suitable for:

- people taking other medicines
- people with serious health conditions, such as liver or kidney disease
- people who are going to have surgery
- pregnant or breastfeeding women
- the elderly
- children – as with all medicines, herbal medicines should be kept out of the sight and reach of children

Speak to your doctor or pharmacist for advice before trying a herbal medicine if you fall into one of these groups.

Are there any serious interactions with gabapentin and other medications?

Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Some examples include narcotic opioids, anti-anxiety medicines, antidepressants, and antihistamines. If you are 65 years of age or older and/or have a condition that affects your lungs, such as chronic obstructive pulmonary disease (COPD), there is an increased risk for breathing problems. Watch for increased sleepiness or decreased breathing when you start taking gabapentin or when the dose is increased. Get help right away if you develop breathing problems.

Seek immediate medical attention if these symptoms develop:

- Confusion.
- Unusual dizziness or lightheadedness.
- Slowed, shallow or trouble breathing.
- Unresponsiveness (can’t wake up).
- Bluish-colored or tinted skin, especially on lips, fingers or toes.

What other medications and products can interact with gabapentin?

Products that interact with gabapentin include:

- Alcohol.
- Antihistamine-containing cold, cough and allergy products.
- Certain medicines for anxiety or sleep.
- Certain medicines for depression, such as amitriptyline, fluoxetine and sertraline.
- Certain medicines for seizures, such as phenobarbital and primidone.
- Certain medicines for stomach problems. (Wait two hours after taking aluminum and magnesium-containing antacids before taking gabapentin.)
- General anesthetics, local anesthetics, or muscle relaxants given before surgery.
- Narcotic pain medicines.

Can I drink alcohol while taking gabapentin?

Avoid drinking alcohol while taking gabapentin. Drinking alcohol with gabapentin could increase sleepiness or dizziness.

Gabapentin Breastfeeding Warnings

Benefit should outweigh risk.

Excreted into human milk: Yes

Gabapentin and breastfeeding

If your doctor or health visitor says your baby is healthy, you can take gabapentin while breastfeeding. It’s important to keep taking gabapentin to keep you well.

Gabapentin passes into breast milk in small amounts. It has not been known to cause any side effects in breastfed babies.

If your baby is not feeding as well as usual, seems unusually sleepy, has a stomach upset, or if you have any other concerns about your baby, talk to your doctor, pharmacist, health visitor or midwife.

Gabapentin and fertility

There’s no evidence to suggest that taking gabapentin reduces fertility in either men or women. However, discuss your pregnancy plans with a doctor. They may wish to review your medicine and prescribe a higher dose of folic acid for you to take (5mg a day) before you become pregnant.

Speak to a pharmacist or your doctor before taking gabapentin if you’re trying to get pregnant.

Comments:
-The effects in the nursing infant are unknown.
-Limited information indicates that maternal doses up to 2.1 g daily produce relatively low levels in infant serum.
-Breastfed infants should be monitored for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs.

You can not take Prescription for a long time, you need find a way to treat your pain without prescription. Exercising is the best way to relieve your pain. because exercising can enhance your immune system and increase your muscle strength and make your nerve strong.

Gabapentin, impotence and other problems?

I was just hoping that you might have the answer I am hoping for?

I started taking gabapentin 300mg twice a day, then 3 times a day, then 600mg twice a day then 3 times a day, now after 2 to 3 years later 800mg 3 times a day.

My doctor says it won’t cause erectile dysfunction but it started very soon after the 300mg 3 times a day. I tried Viagra and Cialis very little help. My wife is very displeased and sometimes thinks it is something to do with her. I know it has nothing to do with her as she is my bride of 24 years and my soul mate spirit. I have very bad pain that the gabapentin used to help with but it now seems it helps no more.

I would rather have my manhood back and my bride be happy and me than be in pain that just won’t go away. To get to the real question, how slowly should I get off the gabapentin and will I ever be able to get back to normal?

I will have to just have to tolerate the pain now that I have my diabetes under control. I rarely have to take my diabetes medicine but a few times a week because it makes my numbers to low and I black out when they get to low.

Usually 82 morning, 92 lunch, and 98 dinner. Any help will be greatly appreciated.

Answers:

Unfortunately gabapentin can cause impotence.

Side effects of the Urogenital System:

Infrequent: urinary tract infection, dysuria, impotence, urinary incontinence, vaginal moniliasis, breast pain, menstrual disorder, polyuria, urinary retention

Rare: cystitis, ejaculation abnormal, swollen penis, gynecomastia, nocturia, pyelonephritis, swollen scrotum, urinary frequency, urinary urgency, urine abnormality.

Talk to your doctor about coming off gabapentin and he/she could put you on some other medicine to help the pain. You don’t have to ween off gabapentin but please get your doctor to monitor you once you are off.

Cautions with other medicines

Some medicines may affect how gabapentin works or increase the chance of you having side effects.

Tell your doctor if you’re taking any of these medicines before you start gabapentin treatment:

strong painkillers, such as morphine – these can make you very tired and dizzy when you start taking gabapentin
antidepressants, such as amitriptyline or fluoxetine
antipsychotic medicines for mental health problems like schizophrenia or bipolar disorder
a medicine to prevent malaria called mefloquine

Gabapentin is used for Restless legs syndrome

Gabapentin in the management of restless legs syndrome (RLS) has been evaluated in small controlled trials, demonstrating benefits compared with placebo.

Restless legs syndrome (RLS) is a condition that causes an uncontrollable urge to move the legs, usually because of an uncomfortable sensation. It typically happens in the evening or nighttime hours when you’re sitting or lying down. Moving eases the unpleasant feeling temporarily.

Restless legs syndrome, also known as Willis-Ekbom disease, can begin at any age and generally worsens as you age. It can disrupt sleep, which interferes with daily activities.

Simple self-care steps and lifestyle changes may help relieve symptoms. Medications also help many people with RLS.

Gabapentin enacarbil is FDA-approved for the treatment of RLS .

The American Academy of Sleep Medicine (AASM) guidelines regarding RLS management consider gabapentin effective based on low-level evidence and note that patients with pain symptoms appeared to benefit most.

The benefit-risk ratio is unclear. The European Federation of Neurological Societies/European Neurological Society/European Sleep Research Society (EFNS/ENS/ESRS) Task Force guidelines consider gabapentin effective for short-term management and possibly effective for long-term management of RLS.

Additional study is needed to establish optimal dosing. Based on the International Restless Legs Syndrome Study Group, European Restless Legs Syndrome Study Group, and RLS Foundation (IRLSSG/EURLSSG/RLS-F) guidelines for the prevention and treatment of dopaminergic augmentation in restless legs syndrome, α2δ ligands (eg, gabapentin) are effective and should be considered for the initial treatment of patients with RLS due to their minimal risk of augmentation.

Additionally, patients who experience augmentation on dopaminergic agents may benefit from a switch to α2δ ligands (eg, gabapentin). However, the guidelines note that long-term studies are needed.

Gabapentin is used for Neuropathic pain (other than postherpetic neuralgia)

In a meta-analysis of trials evaluating the treatment of neuropathic pain, including painful polyneuropathy and spinal cord injury pain, gabapentin was shown to be safe and effective . Data from meta-analyses support the use of immediate-release gabapentin for reducing pain by more than 50% in diabetic neuropathy.

What is neuropathic pain?

Neuropathic pain can happen if your nervous system is damaged or not working correctly. You can feel pain from any of the various levels of the nervous system—the peripheral nerves, the spinal cord and the brain. Together, the spinal cord and the brain are known as the central nervous system. Peripheral nerves are the ones that are spread throughout the rest of your body to places likes organs, arms, legs, fingers and toes.

Damaged nerve fibers send the wrong signals to pain centers. Nerve function may change at the site of the nerve damage, as well as areas in the central nervous system (central sensitization).

Neuropathy is a disturbance of function or a change in one or several nerves. Diabetes is responsible for about 30% of neuropathy cases. It is not always easy to tell the source of the neuropathic pain. There are hundreds of diseases that are linked to this kind of pain.

Data from a limited number of clinical trials support the use of extended-release gabapentin in reducing pain by more than 50% and improving sleep in diabetic neuropathy.

Based on guidelines from the International Association for the Study of Pain (IASP), European Federation of Neurological Societies (EFNS), and Society of Critical Care Medicine (SCCM), gabapentin is effective and recommended for the management of peripheral neuropathy .

Based on guidelines from the EFNS, IASP, and National Institute for Health and Care Excellence (NICE), gabapentin is effective and recommended as first-line therapy, supported by strong evidence, in the management of diabetic neuropathy.

The IASP guidelines recommend both immediate- and extended-release gabapentin . In contrast, a guideline from the American Academy of Neurology (AAN), American Association of Neuromuscular and Electrodiagnostic Medicine, and American Academy of Physical Medicine and Rehabilitation states that gabapentin is probably effective and should be considered an alternative treatment for painful diabetic neuropathy based on limited benefit in 2 controlled trials.

Similarly, a position statement from the American Diabetes Association (ADA) recommends gabapentin as a second-line option .