What you Should Know Before you Buy Gabapentin online

Keep these considerations in mind if your doctor prescribes gabapentin oral capsule for you.

Before taking gabapentin,

tell your doctor and pharmacist if you are allergic to gabapentin, any other medications, or any of the inactive ingredients in the type of gabapentin you plan to take. Ask your pharmacist for a list of the inactive ingredients.
you should know that gabapentin is available in different forms that may be prescribed for different uses. Ask your doctor to be sure that you are not taking more than one product that contains gabapentin.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; antihistamines; medications for anxiety; medications that make you feel dizzy or drowsy; medications for mental illness; naproxen (Aleve, Anaprox, Naprosyn, others); opioid (narcotic) medications for pain such as hydrocodone (in Hydrocet, in Vicodin, others), morphine (Avinza, Kadian, MSIR, others), or oxycodone OxyContin, in Percocet, in Roxicet, others); sedatives; medications for seizures; sleeping pills, and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
if you are taking antacids such as Maalox or Mylanta, take them at least 2 hours before you take gabapentin tablets, capsules, or solution.
tell your doctor if you have or have ever had lung or kidney disease. If you will be taking the extended-release tablets, also tell your doctor if you need to sleep during the day and stay awake at night.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking gabapentin, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking gabapentin.
you should know that this medication may make you drowsy or dizzy, may slow your thinking, and may cause loss of coordination. Do not drive a car or operate machinery until you know how this medication affects you, and your doctor agrees that it is safe for you to begin these activities.
if you are giving gabapentin to your child, you should know that your child’s behavior and mental abilities may change while he or she is taking gabapentin. Your child may have sudden changes in mood, become hostile or hyperactive, have difficulty concentrating or paying attention, or be drowsy or clumsy. Have your child avoid activities that could be dangerous, such as riding a bicycle, until you know how gabapentin affects him or her.
remember that alcohol can add to the drowsiness caused by this medication.
you should know that your mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking gabapentin for the treatment of epilepsy, mental illness, or other conditions. A small number of adults and children 5 years of age and older (about 1 in 500 people) who took anticonvulsants such as gabapentin to treat various conditions during clinical studies became suicidal during their treatment. Some of these people developed suicidal thoughts and behavior as early as one week after they started taking the medication. There is a risk that you may experience changes in your mental health if you take an anticonvulsant medication such as gabapentin, but there may also be a risk that you will experience changes in your mental health if your condition is not treated. You and your doctor will decide whether the risks of taking an anticonvulsant medication are greater than the risks of not taking the medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: panic attacks; agitation or restlessness; new or worsening irritability, anxiety, or depression; acting on dangerous impulses; difficulty falling or staying asleep; aggressive, angry, or violent behavior; mania (frenzied, abnormally excited mood); talking or thinking about wanting to hurt yourself or end your life; withdrawing from friends and family; preoccupation with death and dying; giving away prized possessions; or any other unusual changes in behavior or mood. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Refill

You are only allowed to buy gabapentin online when you refill and you have taken gabapentin before. It means your local doctors have already prescribed you Gabapentin in the past.

Complete the health questionnaires very carefully

your online doctors only know you by your questionnaires. please complete the form very carefully.

General

Gabapentin oral capsules can be taken with or without food. Taking them with food can help to reduce upset stomach.

Storage

Store gabapentin at room temperature between 68°F and 77°F (20°C and 25°C).
Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

Always carry your medication with you, such as in your carry-on bag.
Don’t worry about airport X-ray machines. They can’t hurt your medication.
You may need to show airport staff the pharmacy label for your medication. Be sure to carry with you the prescription-labeled box that your medication came in.
Do not put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Clinical monitoring

Your local doctor will monitor your kidney function.

Gabapentin Dosage Chart, Gabapentin Dosage for Adults and Gabapentin Dosage for Children

Gabapentin is a generic prescription drug that is FDA-approved as an add-on treatment with other medications for partial seizures in those with epilepsy.

It can also be used to treat nerve pain from postherpetic neuralgia (a complication of shingles). Gabapentin is frequently prescribed off-label for many other conditions, such as diabetic peripheral neuropathy, fibromyalgia, and alcohol dependence.

Gabapentin is typically prescribed as a generic, but the drug is also available under the brand names Neurontin and Gralise. Some patients may be prescribed drugs very similar to gabapentin—such as Horizant (gabapentin enacarbil) or Lyrica (pregabalin)—instead of gabapentin.

Gabapentin is taken as a tablet, capsule, or oral liquid. Dosing will depend on the condition being treated, age of the person being treated, and kidney function. The usual dose for epilepsy starts at 300 mg on the first day. The dose can then be increased until an effective dose is reached, which is usually 300 to 600mg taken three times per day.

Gabapentin dosage forms and strengths

Gabapentin is taken by mouth as a tablet, capsule, or oral solution.

- Tablets: 600 or 800 mg per tablet
- Capsules: 100, 300, or 400 mg per capsule
- Liquid: 250 mg per 5 milliliters (ml) oral liquid

Gabapentin dosage for adults

For adults, the gabapentin dosage can vary widely depending on the condition being treated. Upon starting treatment with gabapentin, the starting dose may be 100 to 300 mg per day and steadily increase until an effective dose is reached. The maximum dosage will depend on the condition being treated.

Standard gabapentin dosage for adults: 300-600 mg taken three times per day.
Maximum gabapentin dosage for adults: 1200 mg taken three times per day for a maximum daily dose of 3600 mg.

Gabapentin dosage for children

Gabapentin is FDA approved as a secondary treatment for partial seizures in children 3 years or older with epilepsy. The use of gabapentin in children for any other medical condition is not FDA-approved. Dosing will be determined by both the child’s age and weight.

by both the child’s age and weight.

Gabapentin dosage by age for children older than 3 years
Age (yr)	Recommended dosage
3-4 yrs	40 mg per kg (18.2 mg/lb) of body weight divided into three dosesMaximum: 50 mg per kg (22.7 mg/lb) of body weight daily
5-11 yrs	20-35 mg per kg (9.1-15.9 mg/lb) of body weight divided into three dosesMaximum: 50 mg per kg (22.7 mg/lb) of body weight daily
12 yrs or older	300-600 mg taken three times per dayMaximum: 3600 mg per day

Gabapentin dosage chart
Indication	Age	Standard dosage	Maximum dosage
Partial seizures
	12 years and older	300-600 mg three times per day	3600 mg per day
	5-11 years	25-35 mg/kg (11.4-15.9 mg/lb) per day divided into three daily doses	50 mg/kg (22.7 mg/lb) per day
	3-4 years	40 mg/kg (18.2 mg/lb) per day divided into three daily doses	50 mg/kg (22.7 mg/lb) per day
Postherpetic neuralgia	18 years and older	300 mg on day 1, 300 mg twice daily on day 2, then 300 mg three times daily on day 3; dosage may be further increased after day 3 to 600 mg three times per day	1800 mg per day
Diabetic peripheral neuropathy	18 years and older	300-1200 mg three times per day (off-label)	3600 mg per day
Fibromyalgia	18 years and older	600 mg twice daily and 1200 mg at bedtime (off-label)	2400 mg per day
Alcohol dependence	18 years and older	300-600 mg three times per day (off-label)	1800 mg per day

Gabapentin dosage for partial seizures

Gabapentin is FDA approved as adjunctive therapy for partial seizures in adults and children 3 years of age or older.

Standard gabapentin dosage for adults: 300 to 600 mg taken three times per day by mouth.
Maximum gabapentin dosage for adults: 3600 mg daily in three divided doses.
Renally impaired patients (kidney disease)—dose amount and dose frequency adjustment:
1. Creatinine clearance of 30-59 ml/min: 200 to 700 mg twice per day
2. Creatinine clearance of 16-29 ml/min: 200 to 700 mg once per day
3. Creatinine clearance of 15 ml/min or less: 100 to 300 mg once per day decreased proportionately (1/15 per whole number value) for each decrease in creatinine clearance
4. Hemodialysis: dose is dependent on estimated creatinine clearance; a supplemental dose of 125 to 350 mg is given after dialysis

Gabapentin dosage for nerve pain due to shingles (postherpetic neuralgia)

Gabapentin is FDA approved to treat postherpetic neuralgia, that is, neuropathic pain due to shingles (herpes zoster).

Standard gabapentin dosage for adults: 300 to 600 mg taken three times per day by mouth.

Maximum gabapentin dosage for adults: 1800 mg daily in three divided doses.

Renally impaired patients (kidney disease): See dosage for renal impaired patients above

Gabapentin dosage for neuropathic pain

Gabapentin is most frequently prescribed off-label to treat nerve pain (neuralgia) due to nerve damage (neuropathy), compression, or irritation.

Standard gabapentin dosage for adults: 300 to 1200 mg taken three times per day by mouth.

Maximum gabapentin dosage for adults: 3600 mg daily in three divided doses.

Renally impaired patients (kidney disease): See dosage for renal impaired patients above

Gabapentin dosage for fibromyalgia

Gabapentin is used off-label to reduce fatigue, provide pain relief, and improve sleep in patients with fibromyalgia.

Standard gabapentin dosage for adults: 600 mg twice daily and 1200 mg at bedtime.

Maximum gabapentin dosage for adults: 2400 mg daily.

Renally impaired patients (kidney disease): See dosage for renal impaired patients above

Gabapentin dosage for alcohol dependence

Gabapentin is widely used off-label to reduce insomnia and cravings in people with alcohol use disorder, particularly those in the maintenance phase of alcohol abstinence.

Standard gabapentin dosage for adults: 300 to 600 mg taken three times per day by mouth.

Maximum gabapentin dosage for adults: 1800 mg daily in three divided doses.

Renally impaired patients (kidney disease): See dosage for renal impaired patients above

Gabapentin dosage for pets

You should not give gabapentin to animals unless a veterinarian has given the animal a prescription for gabapentin. Veterinarians frequently prescribe gabapentin to treat seizures or chronic nerve pain in pets and large animals. The recommended dose is 5-10 mg per kilogram of body weight (2.3-4.5 mg/lb) every 12 hours, but dosing will vary between veterinarians. Gabapentin dosages can vary from 3 to 11 mg per kilogram (1.4 to 5 mg per pound) as an analgesic to 10 to 30 mg mg per kilogram (4.5 to 13.6 per pound) as an anticonvulsant. As with people, the dose may start small and steadily increase until an effective dose is reached.

Gabapentin Dosing for Neuropathic Pain

First, we must consider the different neuropathic pain types. Neuropathic pain can be diverse in nature, encompassing a wide range of pain types, including post-herpetic neuralgia (PHN), painful diabetic peripheral neuropathy (DPN), and painful cancer-related neuropathies.

Gabapentin has been shown to be beneficial in treating several types of neuropathic pain; however, the mechanism of action by which gabapentin exerts its analgesic effect is still unknown.

It is suggested that gabapentin may block the calcium channel alpha(2)delta (a2d)-1 receptor in the brain. This protein-modulated receptor is involved in excitatory synapse formation. Therefore, the therapeutic effects of gabapentin may be attributed to prevention of new synapse formations.

Gabapentin was shown to offer substantial improvement in neuropathic pain with side effects that were similar to those on placebo.

Even with sufficient data supporting the use of gabapentin in the treatment of various neuropathic pain conditions, gabapentin only has Food and Drug Administration (FDA) approval for PHN. Dosing recommendations for off-label use of gabapentin can be somewhat ambiguous, if a recommendation exists at all. Therefore, several studies further investigate dosing regimens specific to other neuropathic pain syndromes.

Gabapentin Dosing Considerations

Three gabapentin products are FDA approved to treat PHN. The different formulations cannot be interchanged and each has its own dosing schedule.

- For immediate-release gabapentin (Neurontin), dosing may be initiated with 300 mg on day 1, doubled on day 2 (300 mg twice a day), and tripled on day 3 (300 mg 3 times a day). The dose can then be titrated up as needed for pain relief to a maximum dose of 1,800 mg daily (divided into 3 daily doses). Clinical studies referenced in the package insert state that efficacy for a range of doses from 1,800 mg/day to 3,600 mg/day were observed; however, there was no additional benefit seen with doses greater than 1,800 mg/d.
- Gralise is an extended-release gabapentin formulation that also is FDA approved for PHN with a titration schedule that begins with 300 mg on day 1; 600 mg on day 2; 900 mg on days 3 to 6; 1,200 mg on days 7 to 10; 1,500 mg on days 11 to 14; and 1,800 mg on day 15 and thereafter.
- The third gabapentin formulation for PHN treatment is another extended-release product, Horizant. The starting dose is 600 mg in the morning for 3 days, increased to 600 mg twice daily on day 4 and thereafter. A daily dose of Horizant greater than 1,200 mg provided no additional benefit at the expense of side effects.

Several studies have evaluated off-label use of gabapentin in the treatment of other neuropathic pain conditions. A randomized, double-blind trial compared gabapentin to placebo in 135 patients with DPN over 8 weeks. The results showed a statistical benefit of gabapentin compared to placebo, at all end points, for pain improvement.

The gabapentin dosing regimen used in this study was 900 mg/d for week 1; 1,800 mg/d for week 2; 2,400 mg/d for week 3; and 3,600 mg/d for week 4. All the patients were titrated up to a dose of 3,600 mg/d, regardless of efficacy at lower doses. Patients who could not tolerate this dose were titrated down to the greatest tolerable dose.

Of the 84 patients randomized to the gabapentin group, 56 (67%) were able to tolerate 3,600 mg/d.During the first week, gabapentin resulted in improvement in sleep interference compared to placebo.

By the second week, gabapentin resulted in improvement in all pain rating scales compared to placebo. Of the 84 patients in the gabapentin group, 70 completed the study, and 7 patients withdrew due to adverse drug events (ADEs). Most ADEs reported in the gabapentin group were of mild or moderate intensity, and the most frequently reported effects were dizziness (23.8%), somnolence (22.6%), headache (10.7%), diarrhea (10.7%), confusion (8.3%), and nausea (8.3%).

A double-blind crossover study (n=40) assessed gabapentin for the treatment of DPN. The dose of gabapentin used in this trial was much lower, with patients titrated up every 3 days to a maximum dose of 900 mg/d. The end points evaluated in this study included level of pain on a visual analog pain scale (VAS), and scores on the present pain intensity scale, the McGill pain questionnaire (MPQ), and the global assessment of pain relief.

Statistical improvement between gabapentin and placebo was noted in only 1 end point, the MPQ score, with a mean reduction of 8.9 points for gabapentin compared to 2.2 points with placebo (P=0.03). No serious ADEs were noted, and the most common ADEs of gabapentin were drowsiness, fatigue, and imbalance. The results of this study suggest that gabapentin is not effective or is only minimally effective in treating painful DPN at a dose of 900 mg/d.⁵

A search in the Cochrane Database of Systematic Reviews was conducted to further examine dosing regimens for neuropathic pain. In a review analyzing 37 studies for gabapentin treatment in chronic neuropathic pain, the main outcome was Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) definitions for moderate and substantial benefit in chronic pain studies.⁶ These were defined as follows:

30% reduction in pain over baseline (moderate)
50% reduction in pain over baseline (substantial)
Much or very much improved on Patient Global Impression of Change (PGIC) (moderate)
Very much improved on PGIC (substantial)
Gabapentin was shown to be better than placebo across all studies for IMMPACT outcomes. The review concentrated on gabapentin doses of 1,200 mg/d or greater and reported that doses at or above this threshold were reasonably effective for treatment of various neuropathic pain types.

The upper threshold for maximum effective gabapentin doses ranged from 2,400 mg/d to 3,600 mg/d in the majority of studies reviewed.

ADEs and withdrawal rates for patients taking gabapentin doses of 1,200 mg/d or greater were compared to those for patients taking placebo in 20 studies with 4,125 participants. Common ADEs seen were somnolence, drowsiness, and sedation.

These occurred in 14% of participants in the gabapentin group versus 5% of those taking placebo. Data also showed gabapentin was associated with a higher incidence of dizziness (19% vs 5%), peripheral edema (7% vs 2.2%), and ataxia or gait disturbances (8.8% vs 1.1%).

The rate of serious events was similar between gabapentin and placebo groups. Twenty-two studies involving 4,448 patients reported on participant withdrawals due to ADEs, which occurred in 11% of patients taking gabapentin compared to 7.9% of those taking placebo.⁶

Postmarketing Abuse

Postmarketing reports have described symptoms of agitation, confusion, and disorientation upon abrupt withdrawal of gabapentin. Cases usually involve other potentiating factors, such as the use of higher than recommended doses for unapproved indications, a history of poly-substance abuse, or the use of gabapentin to relieve symptoms of withdrawal from other substances.¹In a study of postmortem toxicology, cases that tested positive for gabapentin or pregabalin were included to determine if abuse of these drugs contributed to the fatalities. Of the 13,766 cases investigated, 0.31% were positive for gabapentin. Of the gabapentin cases, 18.6% were considered abuse, and 4.7% were poisonings. An overwhelming majority of abuse cases (87.5%) also involved opioid intoxication, and 100% involved alcohol and/or opioids. In addition, a greater number of pregabalin cases were designated as abuse cases than gabapentin cases (48.1% vs 18.6%, respectively).⁷

Conclusion

Gabapentin has sufficient evidence showing its efficacy and safety in treating neuropathic pain. Effective treatment doses of gabapentin for neuropathic pain tend to be higher compared to effective treatment doses for other conditions. Gabapentin is a relatively safe medication. The most prevalent effects seen are drowsiness, somnolence, and sedation. It is necessary to start at lower doses of gabapentin and titrate up to a therapeutic dose. Ataxia and somnolence appear to exhibit a positive dose-response relationship; therefore, titrating the dose of gabapentin may help manage possible ADEs.

What Medicines Are Good for Treating Headaches ?

When headache pain has you in its grip, a fast-acting headache remedy is a top priority. Some headache remedies come in the form of medication. But there are also many ways to achieve natural headache relief. Feeling better may require a combination of treatments.

Medications

Headache remedies for migraine headaches are usually prescription drugs, such as:

- beta blockers: atenolol (Tenormin); bisoprolol (Zebeta)
- tricyclics: amitriptyline (Elavil, Endep); doxepin (Adapin, Sinequan)
- calcium-channel blockers: verapamil (Calan, Isoptin, Verelan)
- anticonvulsants: divalproex (Depakote); gabapentin (Neurontin); topimirate (Topamax)
- triptans: almotriptan (Axert); eletriptan (Relpax); sumatriptan (Imitrex).

Triptans are meant for acute treatment of migraines, while all the other categories are meant for chronic prevention of migraines.

You must talk to a doctor in order to get a prescription. The drugs are not available over the counter.

While there are also prescription medications for other types of headaches, such as tension headaches or sinus headaches, over-the-counter (OTC) headache remedies may be enough to relieve the pain they bring. OTC pills are available without a prescription, but as the Harvard Medical School Special Health Report Headaches: Relieving and preventing migraines and other headaches notes, they are medications and must be used carefully.

Acetaminophen (Tylenol and others) is a generally safe non-aspirin headache remedy. But doses above 3 grams per day, especially when combined with alcohol, can cause potentially fatal liver damage. If you consume three or more alcoholic drinks a day, every day, don’t take acetaminophen.

Aspirin quells pain and may prevent migraine headaches in some people when taken regularly. Long-term side effects include kidney damage and gastrointestinal problems, such as stomach pain, heartburn, or nausea. Bleeding from the stomach can also occur, often in such minute quantities as to go unnoticed. However, over time anemia may result, causing fatigue— which, in turn, may increase the frequency of headaches. Avoid aspirin if you have reflux, gastritis, or ulcers.

Nonsteroidal anti-inflammatory drugs (NSAIDs) include aspirin, ibuprofen (Advil, Motrin, others), naproxen sodium (Aleve, Anaprox), and ketoprofen (Actron, Orudis, others). In some people, NSAIDs help prevent migraine headaches. Their long-term side effects are similar to those for aspirin.

Most healthy people who have mild to moderately painful headaches once in a while can take OTC headache remedies. But if you need to take an OTC painkiller several times a week, you should see your doctor.

Natural Headache Relief

Some people feel more comfortable seeking natural headache relief, in the form of plant-based or mineral supplements. Some of the most widely used preparations include:

- - Butterbur, an herb derived from plants in the genus Petasites
  - Feverfew, A daisy-like flower native to Europe
  - Peppermint oil, a culinary herb
  - Magnesium, a mineral
  - Coenzyme Q₁₀, an enzyme found in mitochondria, the energy factories of our cells
  - Vitamin B₁₂

Consult your doctor before taking any of these supplements, as they can interact with medications to treat headaches or other conditions. The FDA does not regulate the effectiveness or safety of these products.

Activities that help

You may need more than just a pill for a headache remedy. Certain activities are also effective at relieving pain. For example, half of all headache sufferers in the United States use some type of mind-body technique to alleviate the pain. These include:

- - meditation
  - relaxation techniques, such as deep breathing
  - yoga
  - hypnosis, a state of deep relaxation that is similar to being in a trance
  - stress management

These mind-body therapies can help lower stress, a widely accepted headache trigger, and they also promote healthier lifestyle habits, such as getting adequate sleep, to keep headaches at bay.

Exercise, if performed regularly, is another natural headache remedy. It helps keep the heart and blood vessels healthy. It also boosts your mood, relieves stress, and helps prevent a host of ailments, such as high blood pressure.

Other natural headache relief

If your own natural headache remedies aren’t effective, consider alternatives, such as:

1. Acupuncture: According to traditional Chinese beliefs, acupuncture works by affecting the flow of energy through pathways that run through the body.
2. Psychotherapy: This can help you manage the effects that headaches have on your life, as well as the stresses and anxieties that may aggravate your pain.
3. Physical therapy: This can provide relief for tension headaches and migraines by relaxing the tense muscles that commonly accompany tension and migraine headaches.

Seeking professional help

If headaches occur on a regular basis, it’s important to speak to your doctor, to see if an underlying condition is to blame, such as a medication side effect or a blood vessel abnormality.

Start with your primary care physician. You may be referred to a neurologist, who might order tests based on your symptoms. Once you have a diagnosis of the causes of your headaches, your doctor will be able to help you devise strategies for effective headache remedies.

Gabapentin is also Used for Prevention of Fibromyalgia

Fibromyalgia is a muscular condition that affects many people. It refers to muscle fatigue and pain felt across different muscle groups in the body, not just on isolated areas. Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues.

The term fibromyalgia directly means pain that is embedded in the tissues of the muscles, specifically the fibrous tissues. This very acute pain starts from the ligaments, the tendons, and other such connective muscle tissues that are present all over the muscular system of the body. Researchers believe that fibromyalgia amplifies painful sensations by affecting the way your brain processes pain signals.

Fibromyalgia Symptoms sometimes begin after a physical trauma, surgery, infection or significant psychological stress. In other cases, symptoms gradually accumulate over time with no single triggering event.

Women are more likely to develop fibromyalgia than are men. Many people who have fibromyalgia also have tension headaches, temporomandibular joint (TMJ) disorders, irritable bowel syndrome, anxiety and depression.

There are however some controversial theories regarding Fibromyalgia that propose that this condition is a psychosomatic illness, that is, it is a disorder brought about by psychological factors and not necessarily physical factors. This reasoning is mainly brought about by the strong evidence available that relates Fibromyalgia to major depression.

An in-depth review regarding the association of major depression disorders with Fibromyalgia brought out significant similarities between the two in terms of psychological characteristics and neuroendoctrine abnormalities in the patients.

Researchers believe repeated nerve stimulation causes the brains of people with fibromyalgia to change. This change involves an abnormal increase in levels of certain chemicals in the brain that signal pain (neurotransmitters). In addition, the brain’s pain receptors seem to develop a sort of memory of the pain and become more sensitive, meaning they can overreact to pain signals.

Medications designed to treat epilepsy are often useful in reducing certain types of nerve pain. Gabapentin (Neurontin) is sometimes helpful in reducing fibromyalgia symptoms. Gabapentin is a medicine used to treat pain caused by nerves that are not working properly. Gabapentin changes the way that the nerves send messages to the brain. It can be taken in a tablet or a liquid, with or without food. Doses are usually 1200 mg to 2400 mg each day. At the start of treatment low doses are used to minimise side effects, but the dose is usually increased after a few weeks.

At the reviews of gabapentin for fibromyalgia in drugs.com , almost 70% Fibromyalgia Patients think Gabapentin can cure their fiobromyalgia disease. But almost 20% fiobromyalgia Patients think it doesnot work. ( Rating 1 -2 %), another 15% patients think it do work but the effect is not that good ( Rating 3 – 5 ).

One of the patient said:

“I have had fibro for 7 years, finally have a doctor that prescribed me Gabapentin. It’s amazing I feel like a normal person again. I sleep through the night, with no pain anymore. My anxiety is gone also, which is awesome. I know everyone is different, but it works for me. I have had little to no side effects yet. First few doses was a bit of an air head other than that no complaints. Being able to function pain free and agitation free is a blessing.”

Another Fiobro patient said:

“I had the best results, in relieving the pain, with gabapentin. I was able to work through the other symptoms. The etodolac helped with the inflammation. I was doing well, until the muscle spasms started, again. I suspect the mould allergies exasperated the symptoms. So, cyclobenzeprine was added. I don’t know what happened, but I was jobless, homeless, and very sick by the time a CVS pharmacist recognized the V.A. had put me on another toxic, prescription drug cocktail. When I brought it to the V.A.s attention, as usual, it was ignored. The medications that help, are the ones the V.A. will not prescribe to veterans like myself. They say speak up, if you do, expect to be classified as mentally ill, violent, aggressive, involuntarily committed”

NatalieW555 Said:
“I was suffering from fibromyalgia pain most of my adult life, I’m 52 by the way, not realizing there was this wonderful medication available to me…I started it about 2 years ago and it really makes a HUGE difference in how my body feels. I take 300 mg 3X daily. I hope it never quits working for me…you should give it a try….It has no side effects on me.”

Member Annabqnm Said:

“Pretty much saved my life. 13 years ago fibromyalgia symptoms (severe pain especially legs and shoulders), started. My father was taking high doses of gabapentin for chronic guillaune barre. He urged me to try it–and it was the first real sleep I had in months! My rheumatologist had me on 1600mg. 3x, gradually lowered to 1600 mg. 2x. Studies at Mayo Clinic and Johns Hopkins show very few (and very mild) side effects, even at high doses. The only problem I have is if I forget to take them. Then I get flu like symptoms. I was able to continue my career (elementary school teacher) with no problems. Retired this year age 66 and very active. BTW my memory seems better than most friends my age.”

But 30% Fibro customers think Gabapentin is not effective for their Fibro disease. I looked the reviews they have wrote, I found most of them are just back pain or leg pain but not Fiobromyalgia. But some Fibro patients do think it has some side effects, especially thought problems such as depression.

One of the Fibro patient said:

“I have “fibromyalgia,” severe muscle pain from a twisted spine/congenitally deformed vertebrae. I was getting better with yoga, but hurt my back/rib muscles overdoing. I developed depression on gabapentin after a few weeks. At first it dulled the pain and made me feel lightheaded, and I had memory problems. Then my anxiety increased and the pain continued, and hit a real low. I spent two weeks in a psych ward until a brilliant psych nurse who believed in treating muscle pain. I am now recovering on a mix of robaxin, a muscle relaxer, a low dose of valium for rib spasms, and prozac and remeron (for sleep) and hope to get off all of them once I can exercise again. Similar reaction to Lyrica four years ago.”

Gabapentin is effective for Fibro. But you need consider whether you can endure the side effects of gabapentin. Please check our website for the Gabapentin Side Effects.

What Should you Know Before you Buy Gabapentin Online

Gabapentin (Generic Neurontin ) was developed to treat epilepsy, but it is now used to treat various forms of chronic pain. It works by reducing the number of signals sent through the nerves. If the signals are reduced then the pain will be reduced. Research has shown that Gabapentin can help in treating various types of nerve pain.

Some Research Team performed searches to look for clinical trials where gabapentin was used to treat neuropathic pain or fibromyalgia. They found that 5633 participants had been involved in 37 studies of reasonable quality. They tested gabapentin against placebo for four weeks or more. Studies lasting only one or two weeks are unhelpful when pain can last for years.

Neuropathic pain is pain coming from damaged nerves. It differs from pain messages carried along healthy nerves from damaged tissue (a fall, cut, or arthritic knee). Neuropathic pain is treated by different medicines than pain from damaged tissue.

Medicines like paracetamol or ibuprofen are not effective in neuropathic pain, while medicines that are sometimes used to treat depression or epilepsy can be very effective in some people with neuropathic pain. Our understanding of fibromyalgia (a condition of persistent, widespread pain and tenderness, sleep problems, and fatigue) is poor, but fibromyalgia can respond to the same medicines as neuropathic pain.

Gabapentin is helpful for some people with chronic neuropathic pain or fibromyalgia. Gabapentin comes as a capsule, tablet, or solution. You take it by mouth. Gabapentin is available as the brand-name drugs Neurontin, Gralise, and Horizant. It’s also available as a generic drug.

It is very important that your doctor check your progress at regular visits, especially in the first few months if you have epilepsy. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

These may be cause serious allergic reactions that may involve multiple organs, such as your liver or kidneys. Check with your doctor right away if you or your child have more than one of the following symptoms: fever, rash, swollen, painful, or tender lymph glands in the neck, armpit, or groin, unusual bleeding or bruising, or yellow eyes or skin.

Gabapentin may cause vision changes, clumsiness, unsteadiness, dizziness, drowsiness, sleepiness, or trouble with thinking. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, or able to think or see well. If these side effects are especially bothersome, check with your doctor.

This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors, such as feeling sad or hopeless, getting upset easily, or feeling nervous, restless, or hostile. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these side effects, tell your doctor right away.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds, sedatives, tranquilizers, or sleeping medicines, prescription pain medicine or narcotics, other medicines for seizures (eg, barbiturates), muscle relaxants, or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you or your child are using gabapentin.

Do not stop using gabapentin without checking with your doctor. Stopping the medicine suddenly may cause seizures. Your doctor may want you or your child to gradually reduce the amount you are taking before stopping it completely.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Can you Legally Buy Gabapentin Online

Neurontin (gabapentin) prescription is not a controlled substance and you can legally buy Gabapentin online with a US licensed doctor prescription.

Our doctors are all US licensed doctors and it will be printed in the label of your prescription bottle.

What you need to do is to answer the questions very carefully and honestly and our USA licensed doctors will decide whether to send you Gabapentin prescription or not.

Yes, you can get a Neurontin (gabapentin) prescription online, in most states, following a virtual consultation with a doctor.

But our website require that you should have already taken Gabapentin before. If it is your first time to take Gabapentin, we will not send you Gabapentin prescription.

You must have your local doctor prescribed a Gabapentin prescription and you think Gabapentin is good for your disease and you can refill your Gabapentin here in our website.

If you have shingles pain or seizures, Neurontin may be able to help you and thanks to modern technology you can get a Neurontin prescription online.

Let’s talk about how you can get a Neurontin prescription online as well as what it is, what it does, what side effects or complications you could experience, and our Neurontin prescription policy.

Where Can I Not Get Neurontin Prescribed Online?

It’s important to note that Neurontin (gabapentin) has been classified as a controlled substance in 5 states and therefore cannot be prescribed online in these locations.

These states are:

- - Kentucky
  - West Virginia
  - Virginia
  - Tennessee
  - Michigan

The Role of Gabapentin in Pain Management

Opioids, non‐steroidal anti‐inflammatory drugs (NSAIDs), antidepressants, and anticonvulsants are used as pharmacological agents to treat pain. However, no single class of drugs has been found to be effective in all types of pain, presumably because pain syndromes involve different mechanisms.

In addition, each of the currently available drugs is associated with adverse effects, some of which are potentially serious or life‐threatening such as idiosyncratic or toxic reactions.

Traditionally, the treatment of neuropathic pain has involved anticonvulsants, such as carbemazepine, valproic acid and phenytoin, and tricyclic antidepressants, such as amitriptyline and nortriptyline and doxepin. The main disadvantages of the anticonvulsants are their potential for drug interactions via the induction of hepatic enzymes, or resulting from inhibition of hepatic enzymes by other drugs. Minor side‐effects such as sedation, ataxia, vertigo and diplopia are associated with carbemazepine and phenytoin, whereas, anorexia, nausea, vomiting and tremor are associated with valproic acid. Chronic phenytoin use may cause peripheral neuropathy (30%) and gingival hyperplasia (20%), and fetal hydantoin syndrome if administered during pregnancy. Carbemazepine can cause chronic diarrhoea or the syndrome of inappropriate ADH secretion, and rarely aplastic anaemia, thrombocytopaenia, hepatocellular jaundice and cardiac arrhythmias.

Tricyclic antidepressants also cause side‐effects that can be troublesome or potentially dangerous, such as anticholinergic effects (dry mouth, blurred vision, urinary retention, ileus), sedation, orthostatic hypotension, tachycardia and atrio‐ventricular conduction disturbances. Such adverse effects are likely to reduce the tolerance of this group of drugs in elderly or unwell patients. Some subgroups of patients with painful neuropathy such as diabetes may also have autonomic neuropathy and may not tolerate the orthostatic hypotension associated with tricyclic antidepressants.

With increasing evidence of the efficacy of gabapentin in a wide variety of pain syndromes, especially neuropathic pain, gabapentin may be potentially useful because of its relative freedom from serious adverse effects, its lack of interactions with other drugs and its lack of potential for causing drug dependence.

A comparison of the evidence available of efficacy and toxicity for anticonvulsants (gabapentin, phenytoin and carbemazepine) and antidepressants (tricyclic antidepressants and SSRIs) in patients with diabetic neuropathy and postherpetic neuralgia has recently been made by Collins et al. [129] These two neuropathic pain conditions were chosen according to strict diagnostic criteria. Although two previous systematic reviews of anticonvulsants and antidepressants in diabetic neuropathy showed no significant difference in efficacy or adverse effects between the two drug classes [130, 131], Collins et al. found that when data from randomised controlled trials for both diabetic neuropathy and postherpetic neuralgia were pooled, the NNT for at least 50% pain relief was identical for both classes of drugs. When gabapentin was compared with other anticonvulsants, there was no significant difference in efficacy.

The NNT for gabapentin was 3.4 compared with 2.2 for phenytoin/carbemazepine. The number needed to harm (NNH, defined as the number needed to harm one patient from the therapy) for minor adverse effects was 2.7 for both antidepressants and anticonvulsants. Collins et al. used two trials to provide data on minor adverse effects for gabapentin and two trials for phenytoin. The NNH (minor adverse effects) was 2.6 similar to that of gabapentin and 3.2 for phenytoin. The NNH (major adverse effects) for the tricyclic antidepressants was 17, and no significant difference in the incidence of major adverse effects was found between anticonvulsants and placebo.

Collins et al. suggested that the difference in the incidence of major adverse effects can be compared by using the ratio between treatment specific benefit and treatment specific harm (defined as the number of patients needed to experience at least 50% benefit for one to experience a major adverse effect that warranted discontinuation of treatment). The ratio for gabapentin was 6 compared with an average of 8 for all anticonvulsants, and 6 for all antidepressants. As adverse data were pooled from both diabetic and postherpetic neuralgia studies, methodological factors and heterogenicity in these data may limit the validity and robustness of these ratios. The spectrum of the pain and short study duration tend to underestimate the treatment effect, whereas the small sample size of the studies overestimate the treatment effect.

The above evidence suggests that gabapentin is as efficacious at treating neuropathic pain with no significant difference in minor adverse effects and a low propensity for serious adverse effects compared with other anticonvulsants and antidepressants. Therefore, gabapentin is a useful agent in the multimodal approach in the management of neuropathic pain.

Returned customer questions and answers

Some returned customers may ask our questions here.

Why you use so many websites ?

Only one website is good enough for you. Our websites are normally hosted by different web hosting providers. Sometimes they may down for no reasons. But as our returned customer, you need read our newsletter and following our newsletter’s websites and emails.

Please do not order in two different websites.

What is your current pharms’s DNS and Refill Days ?

Our current pharms are located in . They all follow US law of refill days and doctor’s licenses. They all have DNS limitation.

Please check the website for their DNS. If you are in the DNS state, I am sure the pharm will not ship to you.

Please also check your refill days. If you refill too soon, the pharm will not send you orders either.

I cannot check every order’s refill days. You need check yourself for your refill days.

Because all our customer data are not stored online, so we cannot send you and reminder for refills.

We really do not have time to find the reasons why the pharm didnot send you orders. Normally they have four reasons:

1. 1. you have sent bounced check;
  2. you did not pick up your last order;
  3. you are in the pharm’s DNS state
  4. you refill too soon.

If you have not recieived your COD orders after four business days, please email me to find the reasons.

Do you need new customers ?

New customers need strict verification and doctor reviews. If you are our returned customer, please go to our returned customer only websites. You will get it from our newsletter.

New customer must verify their address themselves by go to USPS website https://tools.usps.com/go/ZipLookupAction_input

AK customers are all recommended to use P.O. Box to send them orders.

We send each new customer a welcome email. You need reply with “yes ” and we will send you COD order.

The Welcome email :

This is first time you order from us. Just want to confirm whether you really want to pick up this COD order. You are familliar with this prescription and have used this prescription before. All our pharms and doctors are us licensed. The doctors have license in your state too. The State will be a DNS state if the Doctors have no license in that state.

The postman normally deliver the order to your home. Your Address should be OK for postman. You can check your address OK or not in USPS system by clicking: https://tools.usps.com/go/ZipLookupAction_input

We will send you tracking ID within two business days after your confirmation. You can also go to USPS to pick it up if you are not in home. Orders must be picked up and pay the postman USPS money Order not Personnel Check.

Please tell us whether you are OK to pick it up. I will place your order into pharm as soon as I get your reply. New customers need to verify so it may take a longer time. If new customer can not pick up his first order successfully, we will not send him order any more.

Please reply “yes” or “no”

“yes” will begin to process your order.

Thanks
Steve

AK Customers for Gabapentin

AK USPS returned a lot of orders. Please use your P.O Box if you live in AK.