Tag: anticonvulsants

Do I Need Stay on the Same Brand of Gabapentin?

Gabapentin capsules, tablets, and oral solution are used along with other medications to help control certain types of seizures in people who have epilepsy.

Gabapentin capsules, tablets, and oral solution are also used to relieve the pain of postherpetic neuralgia (PHN; the burning, stabbing pain or aches that may last for months or years after an attack of shingles).

Gabapentin extended-release tablets (Horizant) are used to treat restless legs syndrome (RLS; a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down).

Gabapentin is in a class of medications called anticonvulsants. Gabapentin treats seizures by decreasing abnormal excitement in the brain. Gabapentin relieves the pain of PHN by changing the way the body senses pain. It is not known exactly how gabapentin works to treat restless legs syndrome.

Most people do not have to stay on the same brand of gabapentin as there’s very little difference between brands.

Talk to your doctor if you have been asked to switch to a different brand and are worried about that.

If your epilepsy has been hard to control in the past and the brand you’re now taking is working well for you, your doctor may recommend you stay on the same one.

How does Gabapentin Work ?

Gabapentin is a medicine that may be used for the treatment of certain seizure disorders or nerve pain.

Experts aren’t sure exactly how gabapentin works, but research has shown that gabapentin binds strongly to a specific site (called the alpha2-delta site) on voltage-gated calcium channels. This action is thought to be the mechanism for its nerve-pain relieving and anti-seizure properties.

Gabapentin enacarbil (brand name Horizant) is a prodrug of gabapentin which has been designed to overcome the limitations of gabapentin, such as poor absorption and a short duration of action. Gabapentin enacarbil is effective for restless legs syndrome (RLS) and postherpetic neuralgia (nerve pain that occurs following Shingles).

Gabapentin belongs to the group of medicines known as anticonvulsants.

Key facts

  • You’ll usually take gabapentin 3 times a day. You can take it with or without food.
  • Most people who take gabapentin do not get any side effects. But some people may feel sleepy, tired and dizzy. Common side effects are usually mild and go away by themselves.
  • It takes at least a few weeks for gabapentin to work.
  • Most people do not have to stay on the same brand of gabapentin as there’s very little difference between brands.
  • Some people can become addicted to gabapentin after taking it for a long time. When stopping gabapentin you’ll need to reduce your dose gradually to avoid withdrawal symptoms.
  • If you have epilepsy, you are entitled to free prescriptions for all the medicines you take, not just your epilepsy ones. You can get an application form from your doctor’s surgery.

How Long Does it take Gabapentin to Work?

It can take several weeks for gabapentin to reach its full effect, but this depends on the condition being treated.

Gabapentin is approved to treat:

      • Nerve pain
      • Some types of seizures
      • Restless legs syndrome (RLS)

It also depends on your individual response to the drug. The time gabapentin takes to work is not the same for everyone.

The effective dose of gabapentin is also very different for each person. It may vary from 300 mg per day to up to 3,000 mg per day.

Another reason gabapentin takes time to work is that the dose is usually started low and gradually increased over time to reach an effective dose.

For example, when used to relieve nerve pain, the initial dose may be started at 300 mg and increased by 300 mg daily over several days, gradually reaching up to 600 mg three times per day. Studies for nerve pain treatment show that pain relief may begin within 1 week, with the maximum effect reached after about 4 weeks.

Gabapentin is in a class of medications called anticonvulsants. It is not completely known how this drug works. When used to treat a type of seizure disorder, called a partial onset seizure, gabapentin decreases the abnormal activity in the brain that causes the seizures. When used to treat nerve pain, or neuralgia, following a herpes zoster (shingles) infection, gabapentin may reduce the response to painful stimuli. It is unknown how gabapentin relieves symptoms of restless legs syndrome.

Even though it may take up to 4 weeks to get the full effects of gabapentin, it is important not to stop taking it suddenly. That could cause withdrawal symptoms such as:

      • Anxiety
      • Insomnia
      • Nausea
      • Pain

If you are taking gabapentin to control seizures, stopping suddenly may increase your risk of a seizure.

Common side effects of Gabapentin

These common side effects of gabapentin may happen in more than 1 in 100 people. They’re usually mild and go away by themselves.

There are things you can do to help cope with them:

    • Feeling sleepy, tired or dizzy
    • Feeling sick (nausea)
    • Being sick (vomiting)
    • Diarrhoea
    • Mood changes
    • Swollen arms and legs
    • Blurred vision
    • Dry mouth
    • Difficulty getting an erection
    • Weight gain
    • Memory problems
    • Headaches
    • Getting more infections than usual

Keep taking the medicine, but talk to your doctor if this advice does not help and the side effects bother you or do not go away.